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De très nombreux cas cliniques ont été documentés, présentant une grande variété de symptômes et de combinaisons, avec des réponses généralement bonnes au traitement, mais parfois avec des conséquences très graves en cas de prise en charge tardive : pancytopénie, défaillance organique, perte de vision partielle ou permanente, infarctus, et décès
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ketorolac is contraindicated for use in patients with aspirin-sensitive asthma or the aspirin triad because of the approximate 5% cross-sensitivity that occurs between aspirin and NSAIDs
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